Compatible Solute Binding to an Archaeal Inositol Monophosphatase
Chao, Jessica Jade. “Compatible Solute Binding to an Archaeal Inositol Monophosphatase”, Boston College, 2011. http://hdl.handle.net/2345/2216.
Crystallization studies in presence of organic osmolytes were conducted to better understand the specific mechanism of compatible solute binding to the inositol monophosphatase of Archaeoglobus fulgidus. The synthesis of a-diglycerol phosphate, one of the natural osmolytes of A. fulgidus, was also completed for kinetic testing of its I-1-Pase thermoprotective properties and for crystallization trials.