Monoalkylation of 1,2-diols and Design of First Aid Smart Fabrics
Angell, Valerie. “Monoalkylation of 1,2-diols and Design of First Aid Smart Fabrics”. MS, Boston College, 2012. http://hdl.handle.net/2345/3854.
Monoalkylation of 1,2diols: No method for an asymmetric monoalkylation has been previously reported. Attempts here were made to develop this transformation by using a copper catalyst and BOX ligand to impart chirality. Design of First Aid Smart Fabrics: A cellulose filter paper would be linked through a cleavable linker to a bioactive agent. This linker would cleave upon the presence of blood to release the drug directly onto the body.